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Article

Catechol-O-methyltransferase Val158Met polymorphism affects therapeutic response to mood stabilizer in symptomatic manic patients.

Psychiatry research - 30 Jan 2010

Lee Hwa-Young, Kim Yong-Ku

Abstract excerpt

Catechol-O-methyltransferase (COMT) is a candidate gene for the pathogenesis of some psychiatric disorders. The aim of this study is to examine the role of the COMT gene Val158Met polymorphism on the clinical aspects of bipolar disorder including symptomatology and therapeutic response. This study comprised 144 unrelated manic patients who met strict DSM-IV criteria for bipolar I disorder and 157 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20004480
DOI: 10.1016/j.psychres.2008.09.011

Genes

COMT

Provenance

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Catechol-O-methyltransferase Val158Met polymorphism affects therapeutic response to mood stabilizer in symptomatic manic patients.PMID 20004480Read ↗

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The Catechol-O-methyltransferase Val(108/158)Met Genetic Polymorphism cannot be Recommended as a Biomarker for the Prediction of Venlafaxine Efficacy in Patients Treated in Psychiatric Settings.Semantic proximity Read ↗

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Association between catechol-O-methyltransferase Val(108/158)Met polymorphism and psychotic features of bipolar disorder.Semantic proximity Read ↗

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Association Between the COMT Val158Met Polymorphism and Antipsychotic Efficacy in Schizophrenia: An Updated Meta-Analysis.Semantic proximity Read ↗

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