Distribution of the Val108/158Met polymorphism of the COMT gene in healthy Mexican population.

doi:10.1016/j.gene.2013.05.068

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Distribution of the Val108/158Met polymorphism of the COMT gene in healthy Mexican population.

Gene - 10 Sept 2013

González-Castro Thelma Beatriz, Tovilla-Zárate Carlos, Juárez-Rojop Isela, Pool García Sherezada, Genis Alma, Nicolini Humberto, López Narváez Lilia

Abstract excerpt

Catechol-O-methyltransferase (COMT) inactivates the catecholamines adrenaline, noradrenaline and dopamine. On the other hand, some studies have reported that the enzymatic activity of COMT is partly genetically determined. With regard to the COMT gene, the most studied polymorphism is the functional variant Val108/158Met (rs4680), which results in substantial three- to four-fold variations in enzyme activity. To...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Catechol O-Methyltransferase

Share to COMT gene

Share to Gene Frequency

Share to Genotype

Share to Hispanic or Latino

Share to Mexico

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed

Identifiers

PMID: 23774690
DOI: 10.1016/j.gene.2013.05.068

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distribution of the Val108/158Met polymorphism of the COMT gene in healthy Mexican population.PMID 23774690Read ↗

Catechol-O-methyltransferase (COMT) genetic polymorphism in a Turkish population.Semantic proximity Read ↗

Attention-deficit/hyperactivity disorder phenotype is influenced by a functional catechol-O-methyltransferase variant.Semantic proximity Read ↗

The catechol-O-methyltransferase gene: its regulation and polymorphisms.Semantic proximity Read ↗

The Role of a Catechol-O-Methyltransferase (COMT) Val158Met Genetic Polymorphism in Schizophrenia: A Systematic Review and Updated Meta-analysis on 32,816 Subjects.Semantic proximity Read ↗

The Catechol-O-methyltransferase Val(108/158)Met Genetic Polymorphism cannot be Recommended as a Biomarker for the Prediction of Venlafaxine Efficacy in Patients Treated in Psychiatric Settings.Semantic proximity Read ↗

Catechol-O-Methyltransferase (COMT) Val158Met Polymorphism and Eating Disorders: Data From a New Biobank and Meta-Analysis of Previously Published Studies.Semantic proximity Read ↗

Catechol-O-methyl transferase and schizophrenia.Semantic proximity Read ↗

Association between polymorphism of COMT gene (Val158Met) with Alzheimer's disease: An updated analysis.Semantic proximity Read ↗

Val158Met polymorphisms of COMT gene and serum concentrations of catecholaminergic neurotransmitters of ADHD in Chinese children and adolescents.Semantic proximity Read ↗

Genetic polymorphism of catechol-O-methyltransferase (COMT): correlation of genotype with individual variation of S-COMT activity and comparison of the allele frequencies in the normal population and parkinsonian patients in Finland.Semantic proximity Read ↗

The relationship between the val158met catechol-O-methyltransferase (COMT) polymorphism and irritable bowel syndrome.Semantic proximity Read ↗

Role of the COMT gene Val158Met polymorphism in mental disorders: a review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.