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Article

Association of Ala72Ser polymorphism with COMT enzyme activity and the risk of schizophrenia in Koreans.

Human genetics - 1 Mar 2005

Lee Seong-Gene, Joo Yeonho, Kim Byungsu, Chung Seockhoon, Kim Hie-Lim, Lee Inchul, Choi Boyoul, Kim Changyoon, Song Kyuyoung

Abstract excerpt

Catechol-O-methyltransferase (COMT) inactivates circulating catechol hormones, catechol neurotransmitters, and xenobiotic catecholamines by methylating their catechol moieties. The COMT gene has been suggested as a candidate gene for schizophrenia through linkage analyses and molecular studies of...

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Source

Identifiers

PMID: 15645182
DOI: 10.1007/s00439-004-1239-y

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15645182-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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