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Article

CSN-5, a component of the COP9 signalosome complex, regulates the levels of UNC-96 and UNC-98, two components of M-lines in Caenorhabditis elegans muscle.

Molecular biology of the cell - 1 Aug 2009

Miller Rachel K, Qadota Hiroshi, Stark Thomas J, Mercer Kristina B, Wortham Tesheka S, Anyanful Akwasi, Benian Guy M

Abstract excerpt

In Caenorhabditis elegans two M-line proteins, UNC-98 and UNC-96, are involved in myofibril assembly and/or maintenance, especially myosin thick filaments. We found that CSN-5, a component of the COP9 signalosome complex, binds to UNC-98 and -96 using the yeast two-hybrid method. These interactions were confirmed by biochemical methods. The CSN-5 protein contains a Mov34 domain. Although one other COP9...

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Identifiers

PMID: 19535455
DOI: 10.1091/mbc.e09-03-0208
PMCID: PMC2719578

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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