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Article

COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster.

Development (Cambridge, England) - 1 Oct 2002

Oron Efrat, Mannervik Mattias, Rencus Sigal, Harari-Steinberg Orit, Neuman-Silberberg Shira, Segal Daniel, Chamovitz Daniel A

Abstract excerpt

The COP9 signalosome (CSN) is an essential eight-subunit repressor of light-regulated development in Arabidopsis. This complex has also been identified in animals, though its developmental role remains obscure. CSN subunits have been implicated in various cellular processes, suggesting a possible role for the CSN as an integrator of multiple signaling pathways. In order to elucidate the function of the CSN in...

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PMID: 12223399
DOI: 10.1242/dev.129.19.4399

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster.PMID 12223399Read ↗

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A role of Arabidopsis COP9 signalosome in multifaceted developmental processes revealed by the characterization of its subunit 3.Semantic proximity Read ↗

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