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Article

The UNC-45 myosin chaperone: from worms to flies to vertebrates.

International review of cell and molecular biology - 1 Jan 2014

Lee Chi F, Melkani Girish C, Bernstein Sanford I

Abstract excerpt

UNC-45 (uncoordinated mutant number 45) is a UCS (UNC-45, CRO1, She4p) domain protein that is critical for myosin stability and function. It likely aides in folding myosin during cellular differentiation and maintenance, and protects myosin from denaturation during stress. Invertebrates have a single unc-45 gene that is expressed in both muscle and nonmuscle tissues. Vertebrates possess one gene expressed in...

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Identifiers

PMID: 25376491
DOI: 10.1016/B978-0-12-800177-6.00004-9
PMCID: PMC4225561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The UNC-45 myosin chaperone: from worms to flies to vertebrates.PMID 25376491Read ↗

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