Article
The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains.
The Journal of cell biology - 1 Mar 1996
Benian G M, Tinley T L, Tang X, Borodovsky M
Abstract excerpt
Mutations in the Caenorhabditis elegans gene unc-89 result in nematodes having disorganized muscle structure in which thick filaments are not organized into A-bands, and there are no M-lines. Beginning with a partial cDNA from the C. elegans sequencing project, we have cloned and sequenced the un...
Topics
- Amino Acid Sequence
- Animals
- Antibody Specificity
- Base Sequence
- Blotting, Western
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Compartmentation
- Cloning, Molecular
- Fluorescent Antibody Technique, Indirect
- Genes, Helminth
- Helminth Proteins
- Immunoglobulins
- Molecular Sequence Data