Article
The maintenance of neuromuscular function requires UBC-25 in Caenorhabditis elegans.
Biochemical and biophysical research communications - 6 Jun 2003
Schulze Ekkehard, Altmann Maria E, Adham Ibrahim M, Schulze Bettina, Fröde Stephan, Engel Wolfgang
Abstract excerpt
Caenorhabditis elegans gene ubc-25 encodes a novel type of an E2 ubiquitin transferase domain (UBCc) protein, which is highly conserved in multicellular animals, but which is not present in the genomes of fungi or plants. To identify the cellular localization of UBC-25 during the development of C. elegans, we used a ubc-25::gfp reporter gene construct. These experiments showed that ubc-25 expression starts during...
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