Article
Caenorhabditis elegans UNC-98, a C2H2 Zn finger protein, is a novel partner of UNC-97/PINCH in muscle adhesion complexes.
Molecular biology of the cell - 1 Jun 2003
Mercer Kristina B, Flaherty Denise B, Miller Rachel K, Qadota Hiroshi, Tinley Tina L, Moerman Donald G, Benian Guy M
Abstract excerpt
To further understand the assembly and maintenance of the muscle contractile apparatus, we have identified a new protein, UNC-98, in the muscle of Caenorhabditis elegans. unc-98 mutants display reduced motility and a characteristic defect in muscle structure. We show that the major defect in the mutant muscle is in the M-lines and dense bodies (Z-line analogs). Both functionally and compositionally, nematode...
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