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SGAM: an array-based approach for high-resolution genetic mapping in Saccharomyces cerevisiae.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009

Costanzo Michael, Boone Charles

Abstract excerpt

The development of genome-scale resources and high-throughput methodologies has enabled systematic assessment of gene function in vivo. Synthetic genetic array (SGA) analysis automates yeast genetic manipulation, permitting diverse analysis of approximately 5,000 viable deletion mutants in Saccharomyces cerevisiae. SGA methodology has enabled genome-wide synthetic lethal screening and construction of a...

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PMID: 19521818
DOI: 10.1007/978-1-59745-540-4_3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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