Article
Functional Analysis of Kinases and Transcription Factors in Saccharomyces cerevisiae Using an Integrated Overexpression Library.
G3 (Bethesda, Md.) - 10 Mar 2017
Youn Ji-Young, Friesen Helena, Nguyen Ba Alex N, Liang Wendy, Messier Vincent, Cox Mike J, Moses Alan M, Andrews Brenda
Abstract excerpt
Kinases and transcription factors (TFs) are key modulators of important signaling pathways and their activities underlie the proper function of many basic cellular processes such as cell division, differentiation, and development. Changes in kinase and TF dosage are often associated with disease, yet a systematic assessment of the cellular phenotypes caused by the combined perturbation of kinases and TFs has not...
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