Article
Phenotypic activation to discover biological pathways and kinase substrates.
Cell cycle (Georgetown, Tex.) - 1 Jul 2006
Sopko Richelle, Papp Balázs, Oliver Stephen G, Andrews Brenda J
Abstract excerpt
Observing the effects of gene perturbation on cells or organisms has long been a standard strategy in biological research. We developed a genome-wide gene overexpression library as a new tool for large-scale functional analysis in budding yeast. Previous large-scale genetic studies have focused o...
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