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Trigenic Synthetic Genetic Array (τ-SGA) Technique for Complex Interaction Analysis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Kuzmin Elena, Andrews Brenda J, Boone Charles

Abstract excerpt

Complex genetic interactions occur when mutant alleles of multiple genes combine to elicit an unexpected phenotype, which could not be predicted given the expectation based on the combination of phenotypes associated with individual mutant alleles. Trigenic Synthetic Genetic Array (τ-SGA) methodology was developed for the systematic analysis of complex interactions involving combinations of three gene...

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Epistasis, Genetic
Gene Expression Regulation, Fungal
Gene Regulatory Networks
Genes, Essential
Genes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Synthetic

Oligonucleotide Array Sequence Analysis

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PMID: 33733368
DOI: 10.1007/978-1-0716-0947-7_23

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