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Article

Synthetic genetic array analysis in Saccharomyces cerevisiae.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2006

Tong Amy Hin Yan, Boone Charles

Abstract excerpt

Synthetic lethality occurs when the combination of two mutations leads to an inviable organism. Screens for synthetic lethal genetic interactions have been used extensively to identify genes whose products buffer one another or impinge on the same essential pathway. For the yeast Saccharomyces cerevisiae, we developed a method termed Synthetic Genetic Array (SGA) analysis, which offers an efficient approach for...

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PMID: 16118434
DOI: 10.1385/1-59259-958-3:171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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