Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample.

Genes, brain, and behavior - 1 Aug 2009

Hoft N R, Corley R P, McQueen M B, Huizinga D, Menard S, Ehringer M A

Abstract excerpt

The CHRNA6 and CHRNB3 genes have been associated with nicotine dependence and early subjective response to nicotine. Here we present evidence, using a nationally representative sample of adults, that this region is also associated with alcohol behaviors. Six SNPs (single nucleotide polymorphisms) spanning the CHRNB3/A6 genes were analyzed using the statistical genetics software FBAT-PC, which allows one to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Brain Chemistry
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Receptors, Nicotinic

Share to United States

Source

Open in PubMed Open full text

Identifiers

PMID: 19500157
DOI: 10.1111/j.1601-183X.2009.00495.x
PMCID: PMC2880622

Genes

CHRNB3
CHRNA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SNPs in CHRNA6 and CHRNB3 are associated with alcohol consumption in a nationally representative sample.PMID 19500157Read ↗

Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.Semantic proximity Read ↗

Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans.Semantic proximity Read ↗

The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco.Semantic proximity Read ↗

Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women.Semantic proximity Read ↗

Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.Semantic proximity Read ↗

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.Semantic proximity Read ↗

Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence.Semantic proximity Read ↗

Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population.Semantic proximity Read ↗

Significant association of CHRNB3 variants with nicotine dependence in multiple ethnic populations.Semantic proximity Read ↗

CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results.Semantic proximity Read ↗

Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans.Semantic proximity Read ↗

Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.