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Article

Estrogen receptor beta gene variant is associated with vascular dementia in elderly women.

Genetic testing and molecular biomarkers - 1 Jun 2009

Dresner-Pollak Rivka, Kinnar Talia, Friedlander Yechiel, Sharon Nir, Rosenmann Hanna, Pollak Arthur

Abstract excerpt

OBJECTIVE: Alzheimer's disease (AD) and vascular dementia (VaD) are the main causes of dementia. Postmenopausal estrogen deficiency was suggested as a contributor to cognitive decline; however, replacement therapy failed to prove beneficial in its prevention or therapy. Sequence variants in the estrogen receptor alpha gene (ESR1) and beta gene (ESR2) may alter the effects of estrogen. METHODS: This is a...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19473078
DOI: 10.1089/gtmb.2008.0129

Genes

ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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