Estrogen receptor alpha gene variants are associated with Alzheimer's disease.

doi:10.1016/j.neurobiolaging.2010.06.016

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Estrogen receptor alpha gene variants are associated with Alzheimer's disease.

Neurobiology of aging - 1 Jan 2012

Boada Mercé, Antunez Carmen, López-Arrieta Jesús, Caruz Antonio, Moreno-Rey Concha, Ramírez-Lorca Reposo, Morón Francisco Jesús, Hernández Isabel, Mauleón Ana, Rosende-Roca Maiteé, Martínez-Lage Pablo, Marín Juan, Tárraga Lluis, Alegret Montserrat, Pedrajas José Rafael, Urda Nuria, Royo José Luis, Saez María Eugenia, Gayán Javier, González-Pérez Antonio, Real Luis Miguel, Ruiz Agustín, Galán José Jorge

Abstract excerpt

The present research is aimed at assessing the role of 3 estrogen receptor alpha (ESR1) gene variants in late onset Alzheimer's disease (AD) susceptibility. One thousand one hundred thirteen unrelated late onset sporadic AD patients, 1109 healthy controls and 121 neurologically healthy elderly controls were used to carry out case-control genetic association studies with ESR1 rs3844508, rs2234693, and ESR1...

Topics

Join the communities discussing this publication.

Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Aged, 80 and over

Alzheimer Disease

Apolipoprotein E4

Estrogen Receptor alpha

Gene Deletion

Genetic Association Studies

Sex Characteristics

Source

Open in PubMed

Identifiers

PMID: 20674091
DOI: 10.1016/j.neurobiolaging.2010.06.016

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Estrogen receptor alpha gene variants are associated with Alzheimer's disease.PMID 20674091Read ↗

Polymorphisms of the estrogen receptor alpha (ESR1) gene and the risk of Alzheimer's disease in a southern Chinese community.Semantic proximity Read ↗

Study of estrogen receptor-α and receptor-β gene polymorphisms on Alzheimer's disease.Semantic proximity Read ↗

Estrogen receptor beta gene variants are associated with increased risk of Alzheimer's disease in women.Semantic proximity Read ↗

Estrogen receptor α gene polymorphisms and risk of Alzheimer's disease: evidence from a meta-analysis.Semantic proximity Read ↗

Association of the estrogen receptor alpha gene polymorphisms with sporadic Alzheimer's disease.Semantic proximity Read ↗

Estrogen receptor-alpha variants increase risk of Alzheimer's disease in women with Down syndrome.Semantic proximity Read ↗

Association of estrogen receptor alpha (ESR1) PvuII and XbaI polymorphisms with sporadic Alzheimer's disease and their effect on apolipoprotein E concentrations.Semantic proximity Read ↗

Interaction between estrogen receptor 1 and the epsilon4 allele of apolipoprotein E increases the risk of familial Alzheimer's disease in women.Semantic proximity Read ↗

Estrogen receptor polymorphisms and incident dementia: the prospective 3C study.Semantic proximity Read ↗

Association of estrogen receptor alpha gene with Alzheimer's disease: a case-control study.Semantic proximity Read ↗

Association of Estrogen Receptor 1 (ESR1) PvuII and XbaI polymorphisms and peripheral ESR1 mRNA levels with Alzheimer's diseaseSemantic proximity Read ↗

Estrogen receptor α variants affect age at onset of Alzheimer's disease in a multiethnic female cohort.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.