Article
Plasma estrogen levels, estrogen receptor gene variation, and ischemic arterial disease in postmenopausal women: the three-city prospective cohort study.
The Journal of clinical endocrinology and metabolism - 1 Aug 2014
Scarabin-Carré Valérie, Brailly-Tabard Sylvie, Ancelin Marie-Laure, Maubaret Cécilia, Guiochon-Mantel Anne, Canonico Marianne, Scarabin Pierre-Yves
Abstract excerpt
BACKGROUND: In older postmenopausal women, high levels of endogenous estrogen have been related to adverse health outcomes including ischemic arterial disease (IAD). Whether estrogen receptor-α (ESR1) and -β (ESR2) polymorphisms modulate the effects of estrogens on IAD has not been investigated. METHODS: In the Three-City prospective cohort study among subjects older than 65 years, we used a case-cohort design in...
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