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Article

Estrogen receptor β variants modify risk for Alzheimer's disease in a multiethnic female cohort.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Janicki Sarah C, Park Naeun, Cheng Rong, Lee Joseph H, Schupf Nicole, Clark Lorraine N

Abstract excerpt

BACKGROUND: Few studies of gene variants that affect estrogen activity investigate their association with age at onset of Alzheimer's disease (AD) in women of different ethnicities. We investigated the influence of ESR2 polymorphisms on age at onset of AD in a multiethnic cohort of women. OBJECTIVES: To determine whether gene variants would affect risk for AD differently in women of different population...

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Aged, 80 and over
Aging
Alzheimer Disease
Cohort Studies
Estrogen Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

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Identifiers

PMID: 24326520
DOI: 10.3233/JAD-130551

Genes

ESR2
APOE

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