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Article

Mitochondrial complementation preventing respiratory dysfunction caused by mutant mtDNA.

BioFactors (Oxford, England) - 1 Jan 2000

Sato Akitsugu, Nakada Kazuto, Hayashi Jun-Ichi

Abstract excerpt

The mitochondrial theory of aging is the idea that age-associated mitochondrial dysfunction is caused by accumulation of somatic mutations in mitochondrial DNA (mtDNA). However, mitochondria are considered to be a dynamic organelle that repeats fusion and fission. Through fusion and fission, there is an extensive and continuous exchange of mtDNA and its products between mitochondria. This mitochondrial...

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PMID: 19449440
DOI: 10.1002/biof.14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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