Article
Mitochondrial dynamics in heart disease.
Biochimica et biophysica acta - 1 Jan 2013
Dorn Gerald W
Abstract excerpt
Mitochondrial fission and fusion have been observed, and their importance revealed, in almost every tissue and cell type except adult cardiac myocytes. As each human heart is uniquely dependent upon mitochondria to generate massive amounts of ATP that fuel its approximately 38 million contractions per year, it seems odd that cardiac myocytes are the sole exception to the general rule that mitochondrial dynamism...
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