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Article

Caveolin-1 regulation of dynamin-dependent, raft-mediated endocytosis of cholera toxin-B sub-unit occurs independently of caveolae.

Journal of cellular and molecular medicine - 1 Sept 2009

Lajoie Patrick, Kojic Liliana D, Nim Satra, Li Lei, Dennis James W, Nabi Ivan R

Abstract excerpt

Ganglioside GM1-bound cholera toxin-B sub-unit (CT-b) enters the cell via clathrin-coated pits and dynamin-independent non-caveolar raft-dependent endocytosis. Caveolin-1 (Cav1), associated with caveolae formation, is a negative regulator of non-caveolar raft-dependent endocytosis. In mammary epithelial tumour cells deficient for Mgat5, Cav1 is stably expressed at levels below the threshold for caveolae...

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Identifiers

PMID: 19438805
DOI: 10.1111/j.1582-4934.2009.00732.x
PMCID: PMC4516479

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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