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Article

IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.

PloS one - 30 Nov 2010

Salani Barbara, Passalacqua Mario, Maffioli Sara, Briatore Lucia, Hamoudane Meriem, Contini Paola, Cordera Renzo, Maggi Davide

Abstract excerpt

BACKGROUND: Insulin-like growth factor-I receptor (IGF-IR) is a tyrosine kinase receptor (RTK) associated with caveolae, invaginations of the plasma membrane that regulate vesicular transport, endocytosis and intracellular signaling. IGF-IR internalization represents a key mechanism of down-modul...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21152401
DOI: 10.1371/journal.pone.0014157
PMCID: PMC2994771

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21152401-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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