Article
Genetic variation of miRNA sequence in pancreatic cancer.
Acta biochimica et biophysica Sinica - 1 May 2009
Zhu Zheng, Gao Wentao, Qian Zhuyin, Miao Yi
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNAs of 20-22 nucleotides (nts) and constitute a novel class of gene regulators that negatively regulate gene expression at the post-transcriptional level. The expression of miRNA is deregulated in many types of cancers. Alterations in miRNA expression may be an important contributor to the development of pancreatic carcinoma. We hypothesized that genetic variations in...
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