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Article

Novel genetic variants in microRNA genes and familial breast cancer.

International journal of cancer - 1 Mar 2009

Shen Jie, Ambrosone Christine B, Zhao Hua

Abstract excerpt

MicroRNA (miRNA) plays an important role in tumorigenesis, but whether miRNA is a cancer predisposition factor or not is still unknown. Considering the fact that miRNA regulates a number of tumor suppressor genes (TSGs) and oncogenes, genetic variations in miRNA genes could affect the levels of expression of TSGs or oncogenes and, thereby, cancer risk. To test this hypothesis, we screened genetic variants in 17...

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PMID: 19048628
DOI: 10.1002/ijc.24008

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BRCA1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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