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Article

MicroRNA gene polymorphisms in pancreatic cancer.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Jan 2000

Pavlakis Emmanouel, Papaconstantinou Ioannis, Gazouli Maria, Theodosopoulos Theodosios, Karamanolis Georgios, Genatas Konstantinos, Ladas Spiros D

Abstract excerpt

MicroRNAs (miRNAs) act as regulators of gene expression via translational repression. Single nucleotide polymorphisms (SNPs) in miRNAs have been shown to affect the regulatory capacity of miRNAs by influencing miRNA processing and/or miRNA-mRNA interactions. The purpose of this study was to investigate the association between 2 SNPs commonly found in precursor miRNA and the susceptibility and clinicopathological...

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PMID: 23719600
DOI: 10.1016/j.pan.2013.02.005

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