Article

Influence of rs1292037 Genetic Variant on miR-21 Gene Expression in Patients with type 1 Diabetes Mellitus

2021-05-20

Abstract excerpt

<h4>Background: </h4> MicroRNAs (miRNAs) are small non-coding RNA molecules that play a pivotal role in the central dogma of molecular biology by regulating gene expression. Alterations in the expression pattern of miRNAs are seen to be linked with several human diseases including autoimmune diseases such as pediatric type 1 diabetes mellitus (T1DM). Single nucleotide polymorphism (SNP) of the miRNAs coding genes...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9969e4c7-4f4d-526d-a08c-070f220e1492
DOI: 10.21203/rs.3.rs-527664/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Influence of rs1292037 Genetic Variant on miR-21 Gene Expression in Patients with type 1 Diabetes MellitusDOI 10.21203/rs.3.rs-527664/v1Read

Role of microRNA 21 in diabetes and associated/related diseasesSemantic proximity Read

MicroRNA genetic variations: association with type 2 diabetes.Semantic proximity Read

Affection of single-nucleotide polymorphisms in miR-27a, miR-124a, and miR-146a on susceptibility to type 2 diabetes mellitus in Chinese Han people.Semantic proximity Read

The pre-mir-27a variant rs895819 may contribute to type 2 diabetes mellitus susceptibility in an Iranian cohort.Semantic proximity Read

Genetic variants in long noncoding RNA H19 and MEG3 confer risk of type 2 diabetes in an Iranian population.Semantic proximity Read

The Association Between Circulating Levels of miRNA‐181a and Pancreatic Beta Cells Dysfunction via SMAD7 in Type 1 Diabetic Children and AdolescentsSemantic proximity Read

Correlation between rs907715, rs2221903 and rs12508721 polymorphisms in IL-21 and susceptibility to hepatitis B.Semantic proximity Read

CTLA-4 (+49A/G) Polymorphism in Type 1 Diabetes Children of Sudanese PopulationSemantic proximity Read

miR-499a rs3746444 A>G Polymorphism Is Correlated with Type 2 Diabetes Mellitus and Diabetic Polyneuropathy in a Romanian Cohort: A Preliminary Study.Semantic proximity Read

The <i>TH01</i> microsatellite and <i>INS</i> VNTR are strongly associated with type 2 diabetes and fasting insulin secretionSemantic proximity Read

Let-7 related genetic variation and risk of metabolic syndrome in a Chinese population.Semantic proximity Read

The polymorphism in the let-7 targeted region of the Lin28 gene is associated with increased risk of type 2 diabetes mellitus.Semantic proximity Read