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Article

Genetic variations of microRNAs in human cancer and their effects on the expression of miRNAs.

Carcinogenesis - 1 Sept 2008

Wu Meiqun, Jolicoeur Normand, Li Zhen, Zhang Linhua, Fortin Yves, L'Abbe Denis, Yu Zhenbao, Shen Shi-Hsiang

Abstract excerpt

MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the posttranscriptional level to lead to mRNA degradation or repressed protein production. The expression of miRNA is deregulated in many types of cancers. To determine whether genetic alterations in miRNA genes are associated with cancers, we have systematically screened sequence variations in several hundred human miRNAs from >100...

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PMID: 18356149
DOI: 10.1093/carcin/bgn073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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