Article
Single-nucleotide polymorphisms among microRNA: big effects on cancer.
Chinese journal of cancer - 1 Jun 2011
Song Feng-Ju, Chen Ke-Xin
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the transcriptional or posttranscriptional level. Many miRNAs are found to play a significant role in cancer development either as tumor suppressor genes or as oncogenes. Examination of tumor-specific miRNA expression profiles in diverse cancers has revealed widespread deregulation of these molecules, whose loss and overexpression...
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