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Article

Association of tumor necrosis factor-alpha-308 (G-->A) polymorphism and susceptibility to brucellosis.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi - 1 Feb 2009

Reza Jafari-Shakib, Alireza Rafiei, Mostafa Ansari, Alireza Khalilian, Mehrdad Hajilooi

Abstract excerpt

BACKGROUND AND PURPOSE: A critical response against intracellular organisms such as Brucella spp. is production of tumor necrosis factor-alpha (TNF-alpha), which enhances the initial response of infected macrophages. Polymorphism in the TNF-alpha gene promoter has an effect on the level of TNF-alpha production. Therefore, this study investigated the possible association of G-308A polymorphism of the TNF-alpha...

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PMID: 19424555

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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