Article
Tumor necrosis factor alpha -308 gene locus promoter polymorphism: an analysis of association with health and disease.
Biochimica et biophysica acta - 1 Mar 2009
Elahi Maqsood M, Asotra Kamlesh, Matata Bashir M, Mastana Sarabjit S
Abstract excerpt
Tumor necrosis factor-alpha (TNF-alpha) is a potent immunomediator and proinflammatory cytokine that has been implicated in the pathogenesis of a large number of human diseases. The location of its gene within major histocompatibility complex and biological activities has raised the possibility that polymorphisms within this locus may contribute to the pathogenesis of wide range of autoimmune and infectious...
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