Article
Genetic Polymorphism of Tumor Necrosis Factor-Alpha, Interferon-Gamma and Interleukin-10 and Association With Risk of Mycobacterium Tuberculosis Infection.
Journal of evidence-based integrative medicine - 1 Jan 2000
Adane Gashaw, Lemma Mulualem, Geremew Demeke, Sisay Tekeba, Tessema Mekibib Kassa, Damtie Debasu, Ayelign Birhanu
Abstract excerpt
BACKGROUND: Mycobacterium tuberculosis has become the leading cause of morbidity and death in humans worldwide. Thus, genetic variability of the host plays a major role in human susceptibility to the pathogen, among others. Therefore, the objective of this finding was to assess the association of genetic polymorphisms of cytokines with tuberculosis infection. METHOD: A cross-sectional study was conducted between...
Topics
- Case-Control Studies
- Cross-Sectional Studies
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
- Interferon-gamma
- Interleukin-10
- Polymorphism, Single Nucleotide
- Tuberculosis
- Tumor Necrosis Factor-alpha