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Article

TLR4 and TNF-α single nucleotide polymorphisms in patients with brucellosis: Association with infection complications.

European journal of internal medicine - 1 Jan 2025

Giannitsioti Efthymia, Stefos Angelos, Damoraki Georgia, Georgiadou Sarah, Pavlaki Maria, Giamarellos-Bourboulis Evangelos J, Dalekos George

Abstract excerpt

OBJECTIVES: To investigate associations of the carriage of single nucleotide polymorphisms (SNPs) of proteins involved in the immune response of patients with brucellosis. METHODS: A case control study of patients with brucellosis upon WHO criteria. Blood genomic analysis was performed by RFLP- PCR for the detection of SNPs: i) at promoters -376 G > A (rs1800750); -308 G > A (rs 1,800,629); -238 G > A (rs361525)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39419734
DOI: 10.1016/j.ejim.2024.10.006

Genes

TNF
TLR4

Variants

rs1800750
rs1800750

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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