Article
TNFalpha promoter polymorphisms.
Methods in molecular medicine - 1 Jan 2004
Fargion Silvia, Valenti Luca, Dongiovanni Paola, Fracanzani Anna Ludovica
Abstract excerpt
Polymorphisms in the promoter of the tumor necrosis factor alpha (TNFalpha) gene have been reported to affect the transcription rate and the release of this cytokine. Among the best studied, the -238 and -308 polymorphisms have been associated with an increased transcriptional activity and TNFalpha release, whereas the -863 polymorphism have been associated with a reduced transcriptional activity. A growing body...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
