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Article

TNF-α -238, -308, -863 polymorphisms, and brucellosis infection.

Human immunology - 1 Jan 2016

Eskandari-Nasab Ebrahim, Moghadampour Mehdi, Sepanj-Nia Adel

Abstract excerpt

BACKGROUND: Brucella abortus is an intracellular bacterium that affects humans and domestic animals. Tumor necrosis factor-alpha (TNF-α) has been shown as a key player in the induction of cell-mediated resistance against Brucella infection. We aimed to evaluate the possible influence of the TNF-α promoter polymorphisms (-308 G/A, -238 G/A, and -863 C/A) on the susceptibility of human brucellosis. METHODOLOGY: A...

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PMID: 26585363
DOI: 10.1016/j.humimm.2015.11.010

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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