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Article

Meta-analysis of -308G > A polymorphism in TNFα gene and susceptibility to leishmaniasis.

Cytokine - 1 Apr 2021

Ejghal Rajaâ, Charoute Hicham, Talimi Hasnaa, Rhazlane Sara, Lemrani Meryem

Abstract excerpt

The clinical spectrum of leishmaniasis depends on several factors, including Leishmania species and immunogenetic factors. Tumor necrosis factor α (TNFα) plays a central role in immunity against intracellular infections. Many studies have reported that TNFα-308G > A polymorphism is associated with susceptibility to intracellular infections and influences TNFα production. Some studies on the implications of...

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PMID: 33503580
DOI: 10.1016/j.cyto.2021.155437

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