Article
TNFA promoter polymorphism and susceptibility to brucellosis.
Clinical and experimental immunology - 1 Sept 2000
Caballero A, Bravo M J, Nieto A, Colmenero J D, Alonso A, Martín J
Abstract excerpt
The aim of this study was to investigate the possible influence of the tumor necrosis factor alpha (TNFA) gene promoter polymorphisms and HLA class II genes on the susceptibility to or development of human brucellosis. TNFA genotypes (at positions -308 and -238) were determined in 59 patients with brucellosis and 160 healthy controls by polymerase chain reaction-restriction fragment length polymorphism. There...
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