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Article

Abnormal mammary gland development in MMTV-CBLC transgenic mouse.

In vivo (Athens, Greece) - 1 Jan 2000

Fiore Frédéric, Estebe Bruno, Gibier Patrick, Orsoni Jean-Christophe, Courbard Jean-Remy, Chodosh Lewis A, Birnbaum Daniel, Delapeyrière Odile

Abstract excerpt

The CBL family of E3 ubiquitin ligases regulates cell signaling in a number of tissues by promoting degradation of tyrosine kinase receptors such as epidermal growth factor receptor. CBLC, the third member of the CBL family, is expressed in epithelial tissues, including the mammary gland. A transgenic mouse strain expressing a tetracyclin-inducible CBLC in the mammary gland was derived. It was found that CBLC...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Developmental

Share to Mammary Glands, Animal

Share to Mammary Tumor Virus, Mouse

Share to Proto-Oncogene Proteins c-cbl

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Source

Identifiers

PMID: 19414407

Genes

CBLC
CBL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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