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Article

The cbl oncogene: a novel substrate of protein tyrosine kinases.

Australian and New Zealand journal of medicine - 1 Dec 1995

Langdon W Y

Abstract excerpt

The cbl oncogene was first identified as part of a transforming retrovirus which arose in a mouse pre-B cell lymphoma. Its protein product, p120cbl, is cytoplasmic and has several distinctive domains including a highly basic region, a RING finger motif and a large proline-rich domain. A mutation...

Topics

Animals
Caenorhabditis elegans
Cell Line
Cell Transformation, Neoplastic
Humans
Mice
Models, Genetic
Mutation
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-cbl

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Receptors, Antigen, T-Cell

Signal Transduction

Ubiquitin-Protein Ligases

Source

Identifiers

PMID: 8770364
DOI: 10.1111/j.1445-5994.1995.tb02892.x

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8770364-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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