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The role of CBL family ubiquitin ligases in cancer progression and therapeutic strategies

26 Jul 2024

Abstract excerpt

The CBL (Casitas B-lineage lymphoma) family, as a class of ubiquitin ligases, can regulate signal transduction and activate receptor tyrosine kinases through various tyrosine kinase-dependent pathways. There are three members of the family: c-CBL, CBL-b, and CBL-c. Numerous studies have demonstrated the important role of CBL in various cellular pathways, particularly those involved in the occurrence and...

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PMID: 39130630
DOI: 10.3389/fphar.2024.1432545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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