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Article

Cul3 is required for normal development of the mammary gland.

Cell and tissue research - 1 Jul 2021

Cummings Cristina M, Singer Jeffrey D

Abstract excerpt

Cullin 3 (Cul3) has recently been implicated in a multitude of different processes, including the oxidative stress response, autophagy, tumorigenesis, and differentiation. To investigate the role of Cul3 in mammary gland development, we created a mouse model system using Cre-lox targeting where Cul3 is specifically deleted from the mammary gland. Such MMTV-Cre Cul3Flx/Flx mice examined at 2 and 3 months of age...

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Identifiers

PMID: 33825963
DOI: 10.1007/s00441-021-03456-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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