Article
A Drosophila analogue of v-Cbl is a dominant-negative oncoprotein in vivo.
Oncogene - 6 Jul 2000
Robertson H, Hime G R, Lada H, Bowtell D D
Abstract excerpt
Cells rely on the ability to receive and interpret external signals to regulate growth, differentiation, and death. Positive transduction of these signals to the cytoplasm and nucleus has been extensively characterized, and genetic studies in Drosophila have made major contributions to the understanding of these pathways. Less well understood, but equally important, are the mechanisms underlying signal...
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