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Article

Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease.

Inflammatory bowel diseases - 1 Oct 2009

Van Limbergen J, Russell R K, Nimmo E R, Zhao Y, Liao H, Drummond H E, Davies G, Gillett P M, McGrogan P, Bisset W M, Mahdi G, Wilson D C, Brown S J, McLean W H I, Satsangi J

Abstract excerpt

BACKGROUND: Pediatric inflammatory bowel disease (IBD) has a high prevalence of coexistent atopy. Filaggrin (FLG) loss-of-function variants (null-alleles) are associated with eczema and asthma in association with eczema. The aim was to assess the contribution of FLG null-alleles to pediatric IBD susceptibility and to coexistent atopy (eczema, asthma, allergic rhinitis, or food allergy). METHODS: FLG variants...

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Source

Identifiers

PMID: 19408338
DOI: 10.1002/ibd.20926

Genes

FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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