Article
Allergic sensitization and filaggrin variants predispose to the comorbidity of eczema, asthma, and rhinitis: results from the Isle of Wight birth cohort.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Sept 2014
Ziyab A H, Karmaus W, Zhang H, Holloway J W, Steck S E, Ewart S, Arshad S H
Abstract excerpt
BACKGROUND: Allergic sensitization and filaggrin gene (FLG) variants are important risk factors for allergic disorders; however, knowledge on their individual and interactive effects on the coexistence of eczema, asthma, and rhinitis is lacking. OBJECTIVE: This study aimed at investigating the single and combined effects of allergic sensitization and FLG variants on the development of single and multiple allergic...
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