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Article

Predictive value of food sensitization and filaggrin mutations in children with eczema.

The Journal of allergy and clinical immunology - 1 Dec 2011

Filipiak-Pittroff Birgit, Schnopp Christina, Berdel Dietrich, Naumann Aline, Sedlmeier Simon, Onken Anna, Rodriguez Elke, Fölster-Holst Regina, Baurecht Hansjörg, Ollert Markus, Ring Johannes, Cramer Claudia, von Berg Andrea, Bauer Carl Peter, Herbarth Olf, Lehmann Irina, Schaaf Beate, Koletzko Sibylle, Wichmann Heinz-Erich, Heinrich Joachim, Weidinger Stephan

Abstract excerpt

BACKGROUND: It was reported that in infants with eczema and food sensitization, the presence of a filaggrin (FLG) null mutation predicts future asthma with a specificity and positive predictive value of 100%. OBJECTIVES: We sought to evaluate the predictive value of food sensitization and food allergy, FLG haploinsufficiency, and their combination in infants with early-onset eczema for persistent eczema and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22030464
DOI: 10.1016/j.jaci.2011.09.014

Genes

FLG

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