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Article

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.

The Journal of allergy and clinical immunology - 1 Jun 2009

Rodríguez Elke, Baurecht Hansjörg, Herberich Esther, Wagenpfeil Stefan, Brown Sara J, Cordell Heather J, Irvine Alan D, Weidinger Stephan

Abstract excerpt

BACKGROUND: The discovery of filaggrin (FLG) null mutations as a major risk factor for eczema represents a milestone toward the understanding of an important mechanism in this complex disease. However, published studies demonstrate differences concerning design and effect size, and conflicting results for asthma have been reported. OBJECTIVES: We sought to provide a more accurate estimate of FLG effect sizes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19501237
DOI: 10.1016/j.jaci.2009.03.036

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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