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Article

Dynein-driven mitotic spindle positioning restricted to anaphase by She1p inhibition of dynactin recruitment.

Molecular biology of the cell - 1 Jul 2009

Woodruff Jeffrey B, Drubin David G, Barnes Georjana

Abstract excerpt

Dynein is a minus-end-directed microtubule motor important for mitotic spindle positioning. In budding yeast, dynein activity is restricted to anaphase when the nucleus enters the bud neck, yet the nature of the underlying regulatory mechanism is not known. Here, the microtubule-associated protein She1p is identified as a novel regulator of dynein activity. In she1 Delta cells, dynein is activated throughout the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19403691
DOI: 10.1091/mbc.e09-03-0186
PMCID: PMC2704152

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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