Article
The roles of fission yeast ase1 in mitotic cell division, meiotic nuclear oscillation, and cytokinesis checkpoint signaling.
Molecular biology of the cell - 1 Mar 2005
Yamashita Akira, Sato Masamitsu, Fujita Akiko, Yamamoto Masayuki, Toda Takashi
Abstract excerpt
The Ase1/Prc1 proteins constitute a conserved microtubule-associated protein family that is implicated in central spindle formation and cytokinesis. Here we characterize a role for fission yeast Ase1. Ase1 localizes to microtubule overlapping zones and displays dynamic alterations of localization during the cell cycle. In particular, its spindle localization during metaphase is reduced substantially, followed by...
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