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Article

Dynein is regulated by the stability of its microtubule track.

The Journal of cell biology - 3 Jul 2017

Estrem Cassi, Fees Colby P, Moore Jeffrey K

Abstract excerpt

How dynein motors accurately move cargoes is an important question. In budding yeast, dynein moves the mitotic spindle to the predetermined site of cytokinesis by pulling on astral microtubules. In this study, using high-resolution imaging in living cells, we discover that spindle movement is regulated by changes in microtubule plus-end dynamics that occur when dynein generates force. Mutants that increase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28572117
DOI: 10.1083/jcb.201611105
PMCID: PMC5496616

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dynein is regulated by the stability of its microtubule track.PMID 28572117Read ↗

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