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Article

Constitutive dynein activity in She1 mutants reveals differences in microtubule attachment at the yeast spindle pole body.

Molecular biology of the cell - 1 Jun 2012

Bergman Zane J, Xia Xue, Amaro I Alexandra, Huffaker Tim C

Abstract excerpt

The organization of microtubules is determined in most cells by a microtubule-organizing center, which nucleates microtubule assembly and anchors their minus ends. In Saccharomyces cerevisiae cells lacking She1, cytoplasmic microtubules detach from the spindle pole body at high rates. Increased rates of detachment depend on dynein activity, supporting previous evidence that She1 inhibits dynein. Detachment rates...

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Identifiers

PMID: 22535527
DOI: 10.1091/mbc.E12-03-0223
PMCID: PMC3374750

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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